Modelling Nanomaterial Toxicity

MODENA Events 2015

Events in the MODENA Action from 2015 are listed below: 


1. MODENA Workshop - Rome, 5 - 6th May 2015: Knowledge transfer between nanomaterial toxicology & particulate air pollution research.

2. MODENA Training School, Plovdiv, Bulgaria, 20th to 22nd April 2015, (with link to course software, training material and datasets.

3. Sustainable Nanotechnology School, Venice, 11th to 16th January 2015.

Workshop - Rome, 5 - 6th May 2015: Knowledge transfer between nanomaterial toxicology & particulate air pollution research



A MODENA COST workshop will be held to bring together experts in air pollution research and nanotoxicology, with the aim of exchange and to merge the knowledge from the two areas. This will bring together experts in the areas of exposure assessment, dosimetry and toxicology. Those in attendance will discuss the lessons learnt from nanomaterial toxicology that can be applied to air pollution research, and vice versa. 



MODENA Training School, Plovdiv, Bulgaria,  20th to 22nd April 2015.


Location: Hotel Ramada Trimontium, 2 Kap. Raicho str. 4000, Plovdiv, Bulgaria. 

The toxicity of Engineered Nanoparticles needs to be assessed because of the likelihood of these materials coming into contact with humans and the environment. Currently, chemical materials are classified according to their toxicity on a case by case basis. Clearly this is not satisfactory. A more ambitious goal would be a classification rationale for nanomaterials based on their physico-chemical characteristics or common toxic endpoints. An essential step towards this goal would be the creation of mathematical models describing the relationship between the nanomaterial dose, and their physico-chemical characteristics, and the toxic endpoints (e.g. oxidative stress, inflammation). 



These models will facilitate the prediction of the nanomaterial hazard potential, based on their characteristics and can be used to predict by reading across from the results of known materials. By identifying the physico-chemical characteristics driving the toxicity, these models can also help in the design of future nanomaterials which are ‘safe-by-design’. Eventually, the clear advantage of using models for prediction is in the reduction of experiments, in vitro and in vivo.



TD1204 was implemented to support the development of mathematical models for predicting the potential toxicity of engineered nanomaterials. In the second training school for 2015 in Plovdiv (BUL), 20th to 22nd April 2015, we will cover the following: 


  • Materials and their Exposure
    • Nanoparticle Characterisation
    • Human and Environmental Exposure to Nanoparticles
  • Fundamentals of Nanotoxicology
    • Mammalian Toxicology
    • Eco-Toxicology
    • Models of Nanoparticle Toxicity
  • Theory of Modelling
    • Models of Toxicity and Eco-toxicity
    • Practical Sessions


For registration information please contact, who will provide further details. 


22 Trainee Places are available. Interested trainees should send a CV and letter of motivation by 17:00 (UK) on Friday 27th March, to with places being allocated thereafter.


Eligible participants will receive a contribution towards travel and accommodation of up to 560 Euros (less for attendees from Bulgaria).


Participants in the training school need to provide their own their internet enabled laptop computer for use on the course. Wi-Fi will be available at the training venue.



Course software and downloads


The course will make use of the Knime Analytics Platform. Attendees should download and install the software in advance of the course.


The software download is available at : Be sure to download "KNIME + all free extensions".


An introductory tutorial for KNIME is available on YouTube:


A Training Dataset for the workshop is also available for download here.


 Sustainable Nanotechnology School, Venice, 11th to 16th January 2015: Understanding the environmental, health and safety implications of manufactured nanomaterials to foster their sustainable applications. 



A COST MODENA Training School has been arranged in collaboration with the EU FP7 Projects MARINA, GuideNano and SUN, and will take place in Venice from 11th to 16th January 2015.


The First Sustainable Nanotechnology School is especially designed for personnel from research and academic institutions as well as from industry, governmental agencies and hospital departments. The School is aimed at senior researchers, young scientists, PhD students and in fact anyone dealing with nanoscience, nanotechnologies and risk assessment of nanotechnology.

 Further details of the School, registration and scientific programme are available via the local organiser's site at

 As a COST MODENA participant, we will be able to reimburse you for your flight (maximum 300 euros) and a per diem payment of 120 euros towards accommodation and food.

Because of the cost to organise the school in Venice and the duration of the school (Sunday 11th – Friday 16th), the local Venetian organisers have asked for an additional contribution of 150 euros extra towards the administration and organisational cost of the school.

The payment should be made direct to the Venice bank account, see item 4. below.

 If you are happy with this arrangement, then please:

1. Enrol for the Training School (follow the link

2. Let Lang Tran know that you have enrolled (email so that he can keep track of the registrations.

3. Register with COST via the e-cost system for COST reimbursement. Lang Tran will send you an e-mail to inform you when the e-cost system has been opened. This is why you must inform him (via when you have registered with Venice (see 1).

4. Pay your contribution of 150 Euros to        

Account Name: Fondazione Università Ca’ Foscari Venezia

Bank: VENETO BANCA, San Marco 4233 Campo Manin – 30124 Venezia

IBAN: IT93D0503502001084570236326


Payment reason: “Sustainable Nanotechnology School, first edition A.A. 2015” 


We look forward to seeing you at the Training School in Venice.