Modelling Nanomaterial Toxicity

MODENA Events 2016

Events in the MODENA Action in 2016 are listed below...Full details of these meetings will be added as they become available. 


1. Second Sustainable Nanotechnology School, Venice, 24th - 29th January 2016

2. Core Group meeting, Budapest, March 2016

3. Working Group Meeting, Tallinn, May 2016

4. Training School, Archamps, June 2016


1. Second Sustainable Nanotechnology School: A practical approach for understanding the environmental, health and safety implications of manufactured nanomaterials to foster their sustainable applications

Location: University Ca’ Foscari Venice (Italy), campus Via Torino

Dates: 24th - 29th January 2016



A SUN, MODENA COST and ECONANOSORB training school. 


The achievement of safe nanoproducts requires an understanding of the properties, biological interactions, fate, risks and environmental impacts of manufactured nanomaterials. The 2nd Sustainable Nanotechnology School aims to transfer the state of the art knowledge on these aspects from key experts to the new generation nano environmental, health and safety (EHS) professionals. In order to do so the school will highlight the best available experimental and modeling approaches and practices for physicochemical characterization, (eco)toxicity testing, exposure, risk, and lifecycle assessment of nanotechnologies, taking various stakeholder perspectives and ethical issues into account. The 2nd Sustainable Nanotechnology School will revisit and complement the knowledge transferred during the 1st edition of the school with a strong focus on laboratory and modelling exercises.


Full details of the School are available at:  

MODENA COST is able to fund a limited number of trainees to attend this training school. For further information and to apply, please email MODENA's Action Chair, Prof. Lang Tran



2. Core Group meeting, Budapest

Location: La Prima Fashion Hotel Budapest, Hungary

Dates: 8-9th March 2016


This meeting will address planning for the remaining period of TD1204 MODENA. It is only open to members of the Action's MC and Core Group. 


Minutes of this meeting are available upon request from MODENA





3. Working Group meeting: Assessing the dose of nanomaterials in toxicological studies - Advanced approaches utilizing experimentation and modelling

Location: National Institute of Chemical Physics and Biophysics, Tallinn, Estonia

Dates: 4-5th May 2016


In vitro high throughput screening platforms based on mechanistic injury pathways are been used for hazard assessment of nanomaterials (NM). Toxicity screening and other in vitro nanotoxicology assessment efforts in essence compare and rank nanomaterials relative to each other. It has been shown that that this ranking of NM is susceptible to dispersion and dosimetry protocols and partico-kinetics taking place in the in-vitro system, which continue to be poorly standardized. In addition, and this applies both to in vitro studies with submerged cell cultures as well as inhalation studies in rodents, extrapolation to human becomes more reliable when dose and dose rate at the site of depositions is determined accurately.

Mixed experimental/computational approaches to cellular dosimetry can be used by nanoparticle toxicologists to accurately calculate the delivered to cell dose metrics for various NMs and in vitro conditions as a function of exposure time. In addition, in vivo dosimetry models will allow researchers to estimate the delivered dose in any region of the respiratory system and to study the implications of   particle properties and lung function parameters. More importantly, it enables nanoparticle toxicologists to bring to the same level in-vitro and in-vivo doses and help in the development of validated in-vitro cellular screening assays.

The objective of the workshop is to promote the use of emerging particle dosimetry approaches for (inhaled) nanomaterial in-vitro and in-vivo toxicological assessment.  The workshop will include lectures, demonstration activities and exercises.  Presenters are ready to interact with the participants so be prepared for some challenges.


MODENA COST has funded a limited number of delegates to attend this working group meeting. However, if you are interested and wish to participate without funding, please contact Flemming Cassee

4. Training School: Safer-Nano-Design Summer School, 

Location: European Scientific Institute (ESI), Archamps, France

Dates: 12-18th June 2016


"SaferNanoDesign" combines a program of lecture presentations followed up by practical sessions  (experiments, computer simulation and modelling) and interdisciplinary group work. Courses will be given by international experts from France, Scotland, the US, the Netherlands and Switzerland and representatives from industry and regulatory bodies. The working language of the school is English.


Up to 12 grants are available to successful student applicants from COST MODENA, towards the cost of accommodation and travel expenses. To apply, please contact


For further information, please visit:,, or